是一片生物病理方面的论文片断
Table IV shows lifetime risk estimated from all
three studies for which there was an excess ludney
cancer mortality. These are reasonably close, ranging
from 1.3 to 3.1 per 1OOO.
The risk estimates shown in Table IV depend
upon the assumptions made about exposure and the
assumptions as to how long workers were actually
employed. Table V shows lifetime risk estimates for
refinery workers and for distribution workers at various
assumed exposure levels and for various assumed
exposure durations. In parentheses following the occupational
exposures are shown the standardized
lifetime dose, as in Table I. All calculations are based
upon the methods described above.
Table V demonstrates the importance of exposure
levels in establishing the lifetime risk of ludney
cancer from occupational studies. Less important
were the assumptions made regarding duration of
exposure. If average exposures for refinery workers
were somewhere between 5 and 10 PPM then the
estimated lifetime risk for the two positive refinery
worker studies combined ranges from 1.1 to 2.6 per
1000, depending upon the exposure duration assumed.
If average exposures for distribution workers
were between 10 and 15 PPM then the estimated
lifetime risk from that study is 1.3-1.9 per 1000.
These two independent sets of estimates are remarkably
close to each other.
